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Zika prompts FDA to quell blood collection in Florida

Based on Florida’s review into a initial probable locally acquired Zika micro-organism cases in a continental United States, a US Food and Drug Administration (FDA) yesterday asked blood establishments in a dual influenced adjacent counties to immediately stop collecting blood.

In other developments, Zika infection numbers in Puerto Rico continue to arise during a quick clip, along with serve increases in US travelers, including several profound women.

Testing, micro-organism inactivation in blood

The blood collection step, that affects Broward and Miami-Dade counties, is a proxy magnitude to strengthen a blood supply until a blood groups are means to shade any section of blood for Zika RNA or exercise authorized or investigational micro-organism inactivation technology, a FDA pronounced in a matter yesterday.

The Florida Department of Health (Florida Health) is questioning 4 suspected locally acquired Zika cases, dual in any of a counties. In an refurbish today, Florida Health reported dual some-more travel-linked cases, both of them in profound women. Overall, a state has available 328 travel-related Zika cases, and 55 some-more in profound women.

Last week when Florida reported a initial suspected internal case, OneBlood, that provides blood services via Florida and tools of Georgia and South Carolina, pronounced it would start contrast donated blood for Zika micro-organism on Aug 1 regulating a new exam that was postulated puncture use authorization.

Puerto Rico Zika swell continues

In a updated Zika cases numbers for final week, a US Centers for Disease Control and Prevention (CDC) currently reported 914 some-more infections in US territories, many in Puerto Rico. So far, 4,729 have been reported.

In US states, a series of travel-linked Zika cases also climbed during a solid pace, flourishing by 254 from a prior week to a sum of 1,657.

In a refurbish on profound women putrescent with Zika virus, a CDC reported 33 some-more cases in a states and 44 some-more in US territories, putting a totals during 433 and 422, respectively.

One some-more Zika-related birth forsake was reported, in a baby innate in a US state. Overall, a states have now reported 13 inborn Zika cases in newborns, along with 6 pregnancy waste associated to Zika virus. The series in a US territories remained during 1, that reflects a pregnancy loss.

More Caribbean locations affected

In a weekly refurbish on illness developments today, a World Health Organization (WHO) pronounced one some-more nation and one some-more domain have reported internal Zika cases: a eccentric state of Antiqua and Barbuda and a British abroad territories Turks and Caicos.

One some-more country, Paraguay, has reported Zika-liked microcephaly cases, lifting a sum series of influenced nations to 14, a WHO said. It pronounced dual lab-confirmed cases have been reported.

In Guinea-Bissau, where a corner goal is underneath approach to examine internal cases and consider preparedness, one some-more representation has tested certain for Zika micro-organism and 22 additional samples have been collected for testing, a WHO said.

Genetic sequencing tests formula are still tentative on 4 new Zika samples to establish if infections there simulate serve widespread of a Americas aria into another partial of Africa or if a cases engage a African aria that has been on a continent for decades.

Research developments

  • Inovio this week announced that a initial investigate proffer in a proviso 1 hearing has perceived a sip of a Zika DNA vaccine. In a Jul 26 statement it pronounced a trial, that has been privileged by US and Canadian regulators, will take place during clinical sites in Miami, Philadelphia, and Quebec City. It will engage 40 healthy adults and will sign a reserve and immunogenicity of a vaccine administered with Inovio’s exclusive intradermal DNA vaccine smoothness device. The association is building a vaccine, called GLS-5700, with GeneOne Life Science and educational groups in a United States and Canada.
  • In commentary that run opposite to dual new reports, blood and urine tests on 61 Brazilians who were assessed for Zika micro-organism during a strident illness proviso found a aloft showing rate in plasma than in urine. Reporting in Eurosurveillance today, Brazilian and German researchers formed their commentary on tests finished within a initial 5 days of sign onset. Among a patients, 46 were certain on blood tests and 37 had certain urine tests, a disproportion that a group pronounced wasn’t statistically significant. Both samples were certain in 28 patients, and viral loads were identical for both. Earlier studies suggested that a micro-organism lingered longer and in aloft levels in urine. The group pronounced factors specific to a Brazilian race competence explain a difference, and they endorsed contrast of both blood and urine during strident infection.

See also:

Jul 27 FDA press release

Jul 28 Florida Health daily Zika update

Jul 28 CDC update on Zika cases in US states and territories

Jul 28 CDC update on Zika infections in profound women

Jul 28 CDC update on Zika-related pregnancy outcomes

Jul 28 WHO Zika conditions report

Article source: http://www.cidrap.umn.edu/news-perspective/2016/07/zika-prompts-fda-curb-blood-collection-florida

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